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AREVA Med Launches Production of Lead-212 at New Facility

Press Release

November 22, 2013

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CHARLOTTE, N.C., November 22, 2013 – Yesterday, AREVA Med celebrated the opening of the Maurice Tubiana Facility located at Bessines-sur-Gartempe, in the Limousin region of France. After receiving the administrative authorizations and completing the prerequisite technical testing, this unique facility has started production to extract and purify lead-212 (²¹²Pb) for medical use.

This rare metal is used in the development of innovative treatments for certain cancers that do not respond to other conventional methods. As innovation in nuclear medicine is dependent upon the availability of high-purity isotopes, the industrial production at the Maurice Tubiana Facility will provide sufficient amounts of high-purity lead-212 for clinical development. Currently, lead-212 is being used in an AREVA Med Phase 1 clinical trial at the University of Alabama at Birmingham in the United States.

Patrick Bourdet, CEO of AREVA Med, said, “This facility, completed thanks to AREVA’s expertise in radiochemistry and nuclear facility design and the support of our partners, confirms AREVA Med’s industrial development. This will allow us to accelerate the development of alpha radio-immunotherapy using lead-212.”

AREVA Med Contact

Alison Tise

More About AREVA Med

AREVA Med is an AREVA subsidiary specializing in the development of innovative therapies to fight cancer. AREVA Med has developed new processes for producing high purity lead-212 (²¹²Pb), a rare radioactive isotope that is currently at the heart of promising nuclear medicine research.  In 2011, AREVA Med acquired Macrocyclics, the global leader in high performance chelating agent technology.  AREVA Med is also associated with world-class scientific partners, such as the National Cancer Institute (NCI), the University of Alabama at Birmingham (UAB), and the French National Institute of Health and Medical Research (Inserm). In 2012, AREVA Med and Roche entered a strategic alliance to create novel advanced alpha radioimmunotherapy treatments to target and kill certain very aggressive types of cancer cells.  For more information: http://arevamed.areva.com/ or www.targetedtrials.com.